Nichijou Character:Izumi Sakurai

Role:Supporting character

Izumi Sakurai (桜井泉)

A young, shy, and easily frightened teacher. She tries to enforce the school rules to the students albeit unsuccessfully.

Nichijou Character:Kana Nakamura

Role:Supporting character

Kana Nakamura (中村 かな)

A science teacher. She is interested in finding out more information about Nano and Hakase.

In the last episode it is revealed that she was Sakamoto's previous owner and called him "Taisho". She was apparently very clumsy and air-headed and because of it Sakamoto suffered under her care.

Nichijou Character:Sakamoto

• Role:Main character
• Gender: Male
• Hair Color: Black
• Nickname:Sakamoto "Taisho"
• Sakamoto (阪本)
  A black cat who wears a scarf created by the Professor, which allows him to speak. Being technically older than both Nano and the Professor, he speaks in a condescending tone towards them, though he occasionally succumbs to his catlike habits.
  
• In the last episode, it is revealed that Sakamoto used to be Nakamaru's cat and was called "Taisho". Sakamoto does not want to return to Nakamura because she did not take good care of him, even though she had good intentions.
  
• Voice Actors
  Shiraishi, Minoru
  Japanese

Nichijou Character:Nano Shinonome

• Role:Main character
• Gender: Female
• Hair Color:Black
• Nickname:Nano
• Nano Shinonome (東雲なの)
  A robotic schoolgirl that was built by a Professor. She often worries about keeping her identity as a robot from others, despite the fact everyone already knows about it due to the noticeable wind-up key exposed on her back. Luckily most don't make a big fuss about it.
  
  Her limbs will sometimes fall apart, revealing dubious items that Professor has installed without her noticing, ranging from bean-firing-weapons to Swiss rolls. She is also the Professor's caretaker.
  
  She wishes to live life as a normal girl and therefore really wants the wind-up key on her back removed.
  
• In the last episode, after her school friends come over for a surprise birthday party, Nano decides that although the key has been annoying, she prefers things the way they are. The Professor installs a new key on her back that looks the same but spins when Nano is happy.
  
• Voice Actors
  Furuya, Shizuka
  Japanes

Nichijou Character:Hakase Shinonome

• Role:Main character
• Gender: Female
• Hair Color:Orange
• Nickname:Hakase "Professor" Shinonome
• Hakase Shinonome (はかせ)
  An eight-year-old mad scientist who created Nano, often making various adjustments to her without her noticing but never getting round to removing the obvious wind-up key from her back. Despite her intellect, she still acts like any child of her age. Her favorite animal is the shark.
  
• Voice Actors
  Konno, Hiromi
  Japanese

Nichijou Character:Mai Minakami

• Role:Main character
• Gender: Female
• Hair Color: Black
• Nickname:Mai
• Mai Minakami (水上麻衣)
  A rather quiet girl who is very intelligent and often is seen with a book. She is seen to be multi-talented, excelling at using projectiles, arm wrestling, and especially pulling pranks, usually at the expense of Yuuko.
  
• Voice Actors
  Togashi, Misuzu
  Japanese

Nichijou Character:Mio Naganohara

• Role:Main character
• Gender: Female
• Hair Color: Blue
• Nickname:Mio "Mio-chan" Naganohara
• Mio Naganohara (長野原みお)
  A bright and cheerful girl sporting light blue hair and pigtails held by two small wooden cubes. She has a crush on Kojiro. She's usually a calm and collected person who can support her friends whenever they're in a pinch. But she's a lot more sensitive than she lets on, and more often than not needs that support back in return.
  
• She is a fujoshi mangaka.
• Voice Actors
  Aizawa, Mai
  Japanese